TIFR Annual Report, 1993 - 1994

Drosophila neurobiology-anatomy and physiology were studied(Bombay and NCBS collaboration); Synapse Cell Biology -(Drosophila)halothane anaesthesia studies were done, shibire mutation was explored; Neuroanatomy-(Supella longipalpa-cockroach)GAS sensillium discovered; Recombination- Chlamydomonas model used; Biochemistry and Molecular biology-(Yeast) role of 'Aspargine bridge' in pyruvate decarboxylase, (Funaria hygrometrica-Moss) protein kinase, CAM, (moss, corn, sorghum) G-Protein; Malarial parasite- (Plasmodium falciparum, P. vivax) circumporite (CS) antigen;; 7 research groups; Neurobiology of Drosophila- flight muscle development, (mice models used) monoclonal antibodies, proboscis neurons, IP3 pathway in olfaction, cDNA; Gene regulation (mouse model used)- serotonin receptors; Ion channels- (Rana tigrina, R. haemolyticus- frog models) cloned potassium channel cDNA; Protein folding- unusual intermediate in barstar folding; Infectious diseases-(Drosophila) Human papillomavirus in cervical cancer; Highlights : J.R.D.Tata passed away; Dye uptake assay developed; V.Rodrigues visited National University of Singapore;; G.Hasan-Michael Roshbash's laboratory, Brandeis University, Boston-Rockefeller Foundation Fellowship; S.Krishna-Shiv Pillai's laboratory, Massachusetts General Hospital- Rockefeller Foundation Fellowship; J.Udgaonkar-R.Baldwin's laboratory, Stanford University- Rockefeller Foundation Fellowship; Human Papillomavirus research in NCBS; Summary : First annual reports which contain separate mention of the work at NCBS, Frogs, mice and roaches were also used as animal models, Plant studies are seen to be expanding, studies on human cervical cancer were begun at NCBS, several research staff were awarded fellowships to other nations.